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Angiokinase inhibitors : ウィキペディア英語版 | Angiokinase inhibitors Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. Examples include nintedanib (BIBF 1120), afatinib (BIBW 2992) and motesanib (AMG 706). ==History== The term angiokinase was first documented by Auerswald et al. in a paper published in 1971. However, angiokinase inhibitors were not described until 2008 by Hilberg and colleagues.〔 More recently, a number of phase I and II trials have been published, with further phase III trials currently in development.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Angiokinase inhibitors」の詳細全文を読む
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